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Endocrine Disorders in Kidney Disease: Diagnosis and Treatment – Connie M. Rhee

This inaugural edition of Endocrine Disorders in Kidney Disease: Diagnosis and Treatment is dedicated to examining the complex interplay between endocrine and kidney disorders and how this interrelationship impacts patients with chronic kidney disease, including those receiving renal replace­ment therapy in the form of dialysis and kidney transplantation. Indeed, chronic kidney disease patients are a unique population among whom a myr­iad of hormonal derangements may exist. While there has been growing appreciation of this important link between endocrinology and nephrology, many endocrine disorders may remain latent and under-recognized among kidney disease patients.

Hence, this scholarly work is the product of a collaborative effort among experts in areas of endocrinology and nephrology in order to provide a com­prehensive overview of the most relevant endocrine disorders observed in the chronic kidney disease population. Part 1 entitled Diabetes, Insulin, Resistance, and the Metabolic Syndrome presents a practical overview of areas commonly encountered in the clinical management of diabetic kidney disease patients, as well as kidney transplant recipients who develop new onset diabetes. Part 2 entitled Thyroid Dysfunction presents innovative themes pertaining to the high prevalence of thyroid dysfunction in kidney disease, including real-world interpretation of thyroid functional derangements and emerging data on thyroid dysfunction and outcomes in the chronic kidney disease population. Part 3 presents highly pertinent information on Gonadal Disorders, which include testosterone deficiency and other testicular condi­tions, as well as amenorrhea and estrogen disorders in the chronic kidney disease population. Also included in this section is a chapter on pregnancy in kidney disease describing maternal, fetal, and obstetric outcomes, as well as general principles of management. Part 4 entitled Dyslipidemia provides valuable insights into the vast spectrum of lipid disorders associated with chronic kidney disease and nephrotic syndrome, as well as a rigorous sum­mary of existing evidence and clinical practice guidelines addressing the management of dyslipidemia in kidney disease. Part 5 provides an extensive overview of the full-spectrum of Mineral Bone Disorders encountered in kid­ney disease, including calcium, phosphate, fibroblast growth factor 23, vita­min D, and parathyroid hormone alterations; osteoporosis and osteomalacia; and mineral bone derangements observed in kidney transplantation. Emerging data on Obesity and Adipokines in kidney disease are presented in Part 6. Then in Part 7 entitled Other Pituitary Disorders, experts in the field describe pituitary disorders in kidney disease including growth hormone disorders and abnormal stature, as well as prolactin, glucocorticoid, and arginine vasopres­sin derangements. Finally, Part 8 synthesizes many of the aforementioned themes by describing the Multi-System Implications of Endocrine Derangements in Kidney Disease, including endocrine derangements in acute kidney injury, as well as the interaction between nutrition and endocrine dis­orders in kidney disease.

Contents:

Part I. Diabetes, Insulin Resistance, and the Metabolic Syndrome
1. Insulin Resistance and the Metabolic Syndrome in Kidney Disease (e.g., the Cardiorenal Metabolic Syndrome)
2. Diabetic Kidney Disease
3. Glucose Homeostasis and the Burnt-Out Diabetes Phenomenon in Patients with Kidney Disease
4. Glycemic Metrics and Targets in Kidney Disease
5. Diabetic Pharmacotherapies in Kidney Disease
6. Diabetes Mellitus and Renal Transplantation

Part II. Thyroid Dysfunction
7. Evaluating Thyroid Function Tests in Patients with Kidney Disease
8. Thyroid Status and Outcomes in Kidney Disease

Part III. Gonadal Disorders
9. Testosterone Deficiency and Other Testicular Disorders in Kidney Disease
10. Amenorrhea and Estrogen Disorders in Women with Kidney Disease
11. Pregnancy in Kidney Disease

Part IV. Dyslipidemia
12. Lipid Disorders Associated with Chronic Kidney Disease and Nephrotic Syndrome
13. Drugs for Treatment of Dyslipidemia Available in the USA

Part V. Mineral Bone Disorders
14. Calcium Homeostasis in Kidney Disease
15. Phosphorus Retention and Elevated FGF-23 in Chronic Kidney Disease
16. Vitamin D and Parathyroid Hormone in Kidney Disease
17. Management of Bone Disorders in Kidney Disease
18. Mineral and Bone Disorders Following Renal Transplantation

Part VI. Obesity and Adipokines
19. Obesity in Kidney Disease
20. Adiponectin and Leptin in Kidney Disease Patients

Part VII. Other Pituitary Disorders
21. Growth Hormone Disorders and Abnormal Stature in Kidney Disease
22. Other Pituitary Disorders and Kidney Disease
23. Endocrine System in Acute Kidney Injury
24. Nutrition and Endocrine Disorders in Kidney Disease
Index

Formato:  pdf Comprimido:  rar Peso:  9.04 MB Lenguaje:  Inglés

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